Rick and Rio's Mother

Another 2003 anime exclusive character, the mother of Rick and Rio (real name unknown) was a woman living in Ishval with her sons. During the Ishval Civil War, their house was attacked by the Amestrian military, and she ran away seemingly ignoring the boys, only to get killed in an explosion. She left behind a locket that Rick kept treasuring the memories of his mother, while Rio, who saw her run away, believed that she had abandoned them. Later, when the locked was damaged and opened, some eye medicine was found inside (along with a photo of Rick and Rio with their mother), and it was revealed that the boys' mother suffered from an eye disease which didn't let her see her children when the house was attacked, prompting her to run into their room to look for them.