User blog comment:Jon825lazery7/Sleim Bradley's/Pride's Speech/@comment-1618178-20121223125121

Yeah, it is!

In a way, Father is Hohenheim's son, since he was created with the blood of Hohenheim and, therefore, Pride would be "Ed's nephew". But that's all in the figurative sense of the whole deal, since they are all homunculi, not people, really. Moreover, Pride has also the souls of all other Xerxes people, so only a part of him is related to Hohenheim and Ed.