User blog comment:Kiadony/Not leaving =)/@comment-1318060-20100710185046

Al and Roy can still use alchemy without Transmutation Circles. Edward will likely never be able to use any sort of transmutation ever again, since he destroyed his own gate. And, no, I doubt seriously that Arakawa's next work will have anything at all to do with the Fullmetal Alchemist universe, though the Brotherhood movie that they've recently announced might follow Al or something like that, so long as it isn't simply a movie retelling.