Mrs. Tucker

She was wife of Shou Tucker and mother of Nina Tucker. She lived in poverty with her husband and daughter prior to Shou Tucker becoming a State Alchemist. She became fed up with living in poverty and Shou's obsession with studying alchemy and threatened to leave him. It was at that point that Shou used Mrs. Tucker and transmuted her with an unknown creature(supposedly a dog, as in the image below left but she could've been combined into more that one creature soul) to form a talking chimera.

As a Chimera
The first chimera created by Shou Tucker, made from his wife. Roy Mustang said that it only said one sentence, yet was able to talk.

"I want to die".

After that, it stopped eating and died shortly afterwards of suffering in the form of a chimera.

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 * [Tucker Family]