Iron and Flame

Iron and Flame was a Fullmetal Alchemist flash game formerly hosted on the [adult swim] website. The player was able to control both Edward and Alphonse Elric, who were sent by Roy Mustang to destroy the last of Shou Tucker's remaining chimeras.

Gameplay
The game was played from a side-scrolling perspective. The player was able to control one of the two protagonists and could switch between them at any time. The character which was not being used by the player would be controlled by the computer. Each of the two characters was capable of using melee attacks as well as a number of alchemical transmutations. Most of these transmutations needed to be unlocked, as each character only started with one. Edward had a total of eight slots for transmutations in his alchemy menu, while Alphonse had four, and the player could bind up to three keys to any three transmutations for each character.

Game Developer
http://thisispop.com